Guanidinium Chloride-Induced Haemolysis Assay to Measure New Permeation Pathway Functionality in Rodent Malaria Plasmodium berghei
Parasite-derived new permeation pathways (NPPs) expressed at the red blood cell (RBC) membrane enable Plasmodium parasites to take up nutrients from the plasma to facilitate their survival.Thus, NPPs represent a potential novel therapeutic target for malaria.The putative channel component of the NPP in the human malaria parasite P.falciparum is enc